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Memory loss, Alzheimer’s screening and how to keep your mind sharp

As you age, you may start noticing memory loss such as you can’t recall people’s names as quickly or you misplace your keys a little more often.

Graphic of man scratching his head having trouble with memory loss
Talk to your doctor about memory loss when it starts to interfere with daily life.

“These memory slips usually aren’t cause for concern, but talk to your doctor when memory problems interfere with daily life,” said Dr. Sarah Kortenkamp, a Marshfield Clinic neuropsychologist. “Even if your memory problems are caused by normal aging, your primary care doctor will be able to take steps to determine your baseline so it’s easier to detect if things get worse.”

Common memory loss vs. Alzheimer’s symptoms of concern

As people age, they may become less physically and mentally agile, but it doesn’t always mean it’s Alzheimer’s disease.

Doctors should ask about cognitive changes during Medicare wellness visits. Typically, this includes a mini mental status test, like asking a patient to name as many objects as they can think of.

“We often use the AD8 to screen patients,” said Dr. Jason Kanz, a Marshfield Clinic neuropsychologist. “If there is a change in two or more of these items, it may be associated with clinically significant impairment.”

Ascertain Dementia 8-item Informant Questionnaire

The AD8, The Ascertain Dementia 8-item Informant Questionnaire, asks a patient or loved to answer questions to evaluate whether a person has:

  1. Problems with judgment (e.g., problems making decisions, bad financial decisions, problems with thinking)
  2. Less interest in hobbies/activities
  3. Repeats the same things over and over (questions, stories or statements)
  4. Trouble learning how to use a tool, appliance or gadget (e.g., VCR, computer, microwave, remote control
  5. Forgets correct month or year
  6. Trouble handling complicated financial affairs (e.g., balancing checkbook, income taxes, paying bills)
  7. Trouble remembering appointments
  8. Daily problems with thinking and/or memory

Doctors begin asking these questions around ages 60 to 65. In this age range, 1-2 percent of people show symptoms of Alzheimer’s disease. By age 85, this increases to 40-50 percent. Some early memory loss develops into dementia, while other symptoms do not.

“Just pay attention to your memory,” he said. “As we age, our brains become less efficient. That’s normal. But you should identify significant changes as soon as possible and share with a doctor.”

Normal cognitive difficulties Symptoms of concern
Able to function independently and pursue normal activities, despite occasional memory lapses. Difficulty performing simple tasks like paying bills, dressing appropriately. Forgetting how to do things you’ve done many times.
Pausing to remember directions, but not getting lost in familiar places. Gets lost or disoriented in familiar places.
Occasional difficulty finding the right word, but no trouble holding a conversation. Words are frequently forgotten, misused or garbled. Repeats phrases and stories in the same conversation.
Sometimes forgetting where you left things you use regularly, such as glasses or cell phone. Misplacing items in inappropriate places, such as putting a wallet in a kitchen drawer.
Forgetting where you put your keys. Forgetting what your keys are for.
Forgetting parts of an experience. Forgetting an entire experience.
Forgetting where you park the car. Forgetting how to drive a car.
Forgetting names of acquaintances or blocking one memory with a similar one (for example, calling a grandson by your son’s name). Forgetting ever having known a person.
Becoming easily distracted or having trouble remembering what you’ve just read, or the details of a conversation. Loss of function, confusion or decreasing alertness.

Your overall health can impact your brain and memory

 Your brain health is important, and there are ways you can support it as you age.

 1Regular exercise

“Generally, research shows an effective way of maintaining peak brain function is through regular physical activity,” Kanz said.

A sharp brain depends on operation of blood vessels. Exercise boosts blood flow through the body and the brain, which is essential for brain cells to operate effectively.

“Incorporating exercise at least four times a week is going to reduce your risk of cognitive decline,” Kanz said. “And it’s OK to split it up throughout the day, such as 15 minutes in the morning, afternoon and evening.”

Cognitive activity

“Brain training” programs and apps have gained popularity in recent years, claiming to delay age-related memory loss and prevent against diseases like Alzheimer’s.

In January 2016, the Federal Trade Commission (FTC) stated programs like Lumosity deceive customers, and there is not enough research to support these applications benefit memory.

“Though there’s not enough research to prove such apps and games improve memory, there is evidence to suggest cognitive activity can be beneficial. Doing something out of the ordinary, getting your brain to think differently, can help keep your mind sharp.”

Play board games, learn a musical instrument or take up a new hobby. These activities help you stay engaged, learn new things and challenge yourself. These healthy habits add up to neuroplasticity, or your brain’s ability to function and adapt to change.

Social interaction benefits the brain. Older adults who maintain social connections tend to do better on memory tests, Kanz said.

Balanced nutrition

A well-balanced diet can keep the mind and body healthy. The MIND diet has been gaining momentum for its ability to help boost brainpower and protect the brain from age-related problems like Alzheimer’s disease. The MIND diet focuses on minimally processed and plant-based foods. It limits animal-based foods that are high in saturated fats and foods with added sugars. A prominent component of the diet is leafy green vegetables.

Medications and treatments

There is no research that shows over-the-counter medications can boost memory or slow down memory loss. Some of them contain chemicals important for memory, but those chemicals fail to reach the brain when taken orally. Vitamin D can affect memory, but it will only benefit someone who is vitamin D-deficient.

There are several memory stabilizing medications and antibody therapy infusion treatments that can slow memory decline in people with early to mid-stage dementia. They do not improve memory but can slow down the course of disease.

Learn more brain health tips in this video:

For questions about brain health, talk to a Marshfield Clinic Health System provider.

Schedule appointment Message your provider

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15 responses to “Memory loss, Alzheimer’s screening and how to keep your mind sharp”

  1. Susan

    Many seminars on Dementia i have attended utilize PET scans. Does MC include them in the assessment and or ongoing treatment plan?

    1. Jordan Simonson

      Hi Susan, Yes, Marshfield Clinic Health System does us PET scans as part of work-ups for dementia within our Memory Disorders Clinic. -Thank you, Jordan

  2. Sue

    Are there any otc medications that would help slow down the memory issues like prevagen?

    1. Jordan Simonson

      Hi Sue, Dr. Kortenkamp provided this response to your question: "There is no research showing Prevagen works to boost memory or slow down memory loss. The main ingredient is a chemical that seems important for memory, but taken orally it likely immediately breaks down in stomach acids and never reaches the brain. It is a scam and a waste of money. It also contains Vitamin D. Low vitamin D levels can affect memory, so a supplement may help in people who have low levels. There are much less expensive vitamin D supplements available.

      There is no evidence vitamin D or other over the counter supplements (Vit E, B12, etc.) benefit memory unless bloodwork shows a deficiency. Research for other supplements (e.g., ginko balboa) is lacking, but so far there is no good evidence anything else over the counter helps.

      There are several prescription medications that can slow memory decline in people with early to mid-stage dementia. The treatment benefits are subtle and do not lead to improvements in memory, but they can slow down the course slightly (a few months to years). Your doctor can give you more information about these treatments." Thanks for the question! -Jordan

  3. Donna Raubal

    I have some problems completing sentences or finding the right word sometimes. This happened when I started with other fibromyalgia problems, (pain, fatigue, sleep difficulty, etc.). Some articles I have read say that 'fibro brain' is just part of the condition. I will be 80 in a short time and haven't really seen any change since my 60's in how I construct sentences or recall names.

  4. Michelle

    Are any studies being done on the long-term effects of chemotherapy and memory loss (chemonesia)?

    Shortly after I began receiving chemo treatments for breast cancer, I began having memory problems, particularly with accessing words. When my chemo treatments ended, the problem improved, but has never completely disappeared. It's not as frequent now, but I continue to have trouble remembering/accessing words. It is very frustrating to have common words simply disappear in the middle of speaking a sentence.

    1. Kirsten Shakal, Shine365 Editor

      Hi, Michelle. According to our Shine365 story "Chemo brain: A real, manageable cancer treatment side effect," “This is an area that is not well-studied,” said Dr. Gayle, Marshfield Clinic oncologist. “There aren’t randomized clinical trials to say exactly what you should do. We need more studies looking at patients going through chemotherapy at different ages and assessing the biochemical changes that occur.”

      You can read more about "chemo brain" here – https://shine365.marshfieldclinic.org/cancer-care/chemo-brain-a-real-manageable-cancer-treatment-side-effect/

      Discuss further memory concerns with your doctor. If you are a Marshfield Clinic patient, you can also message your care team via My Marshfield Clinic: https://my.marshfieldclinic.org/ -Kirstie

      1. Michelle

        I've been discussing this issue with my doctor, so that end is covered. Thanks for the link to the article. I had suspected that the area wasn't much studied, but hadn't thought about it in terms of pre-testing to evaluate changes.

        On my own, I was playing more mentally-stimulating games while in treatment, including Sudoku, games from Luminosity, and Dots to help keep my mind focused and active. I like to think it helped.

        I hope someone is considering this area of research. Chemonesia/chemo brain is no fun! There are many people who would benefit from such a study.

  5. FLASHg

    I share Lois C.'s question.

    1. Kirsten Shakal, Shine365 Editor

      FLASHg, please see the response below. I hope this helps answer your question. -Kirstie

  6. Lois Corey

    will an MRI reveal Alz/dementia problems?

    1. Lillian Anglemyer

      I would like to know the same as Lois C

      1. Kirsten Shakal, Shine365 Editor

        Hi, Lillian. I have replied to Lois below. Thanks for reading. -Kirstie

    2. Kirsten Shakal, Shine365 Editor

      Hi, Lois. I shared your question with Stuart Waltonen, PhD, Neuropsychology. Here is what he had to say on MRIs and Alzheimer's:

      MRI does not contribute significantly to the accuracy of an Alzheimer’s diagnosis over a doctor’s clinical assessment of the patient’s symptom pattern and history of symptom onset alone. By the time the MRI can detect changes within the brain in a patient with Alzheimer’s, the patient’s symptoms and the observed progression of symptoms over time have already confirmed the diagnosis.

      There is some preliminary research suggesting the MRI may help with predicting the rate of decline in patients with Alzheimer’s but there is not enough research evidence at this time to warrant using the MRI for this purpose.

      An MRI of the brain can help rule out other neurological disorders causing the patient’s symptoms, such as a brain tumor or stroke, to name a couple of common disorders, which then allows doctors to arrive at an Alzheimer’s diagnosis more quickly.

      -Kirstie

      1. Lois Corey

        Thank you very much for your time and information! Lois

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